Hepatitis E Virus Seroprevalence and Chronic Infections in Patients with HIV, Switzerland
- Alain Kenfak-Foguena
- Franziska Schöni-Affolter
- Philippe Bürgisser
- Andrea Witteck
- Katharine E.A. Darling
- Helen Kovari
- Laurent Kaiser
- John-Marc Evison
- Luigia Elzi
- Vanina Gurtner De La Fuente
- Josef Jost
- Darius Moradpour
- Florence Abravanel
- Jacques Izopet
- Matthias Cavassini
Publication date
June 2011
DOI Publisher
Centers for Disease Control and Prevention (CDC) Journal
Emerging Infectious DiseasesAbstract
We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation
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