External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil
- Carlo Fischer
- Celia Pedroso
- Alfredo Mendrone
- Ana Maria Bispo de Filippis
- Antonio Carlos Rosário Vallinoto
- Bergmann Morais Ribeiro
- Edison Luiz Durigon
- Ernesto T.A. Marques
- Gubio S. Campos
- Isabelle F.T. Viana
- José Eduardo Levi
- Luciano Cesar Scarpelli
- Mauricio Lacerda Nogueira
- Michele de Souza Bastos
- Nathalia C. Santiago Souza
- Ricardo Khouri
- Sanny M. Costa Lira
- Shirley Vasconcelos Komninakis
- Cécile Baronti
- Rémi N. Charrel
- Beate M. Kümmerer
- Christian Drosten
- Carlos Brites
- Xavier de Lamballerie
- Matthias Niedrig
- Eduardo Martins Netto
- Jan Felix Drexler
Publication date
May 2018
DOI Publisher
Centers for Disease Control and Prevention (CDC) Journal
Emerging Infectious DiseasesAbstract
We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is required for adequate estimates of Zika virus–associated disease and determination of patient care
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