Add to ORKGThe new drugs introduction in practice demands long multistage preliminary studying of efficacy and safety for children. The information on necessity of carrying out of such researches, on impossibility of «carrying over» of the data received in adult patients to children is given in this article. The historical inquiry confirming necessity of participation of the state for the decision of this problem and carrying out of clinical researches is presented. Key words: drugs, efficacy, safety, clinical trials, children. (Pediatric Pharmacology. – 2010; 7(1):6-14
There have been numerous studies to show that many of the medicines used in children are used off-la...
Knowledge of drug administration in children and infants lags behind that of adults for many reasons...
textabstractInterest in pediatric pharmacology has increased over the past two decades. With few exc...
The new drugs introduction in practice demands long multistage preliminary studying of efficacy and ...
Children were acknowledged as ‘therapeutic or pharmaceutical orphans’ in 1960s, since then there has...
Most drugs lack information on their safe and effective use in children. This dilemma limits the num...
Children often have to accept treatments based on what is known to work in adults. Many efforts are ...
Purpose Few data on the efficacy and safety of drugs in children are available as in the past, these...
Ethics and recruitment issues Evidence-based medicine and healthcare are the pillar of optimal medic...
Drug therapy is a very powerful tool to improve the medical outcome of children. Despite this fact, ...
Despite international initiatives to promote clinical research in pediatrics, there are still many g...
Purpose A dearth in pediatric drug development often leaves pediatricians with no alternative but to...
the present review is devoted to an actual problem of safety of pharmacotherapy in clinical practice...
This paper is focused on the most prominent problems of the contemporary pediatric pharmacotherapy: ...
textabstractMany commercially available drugs are only licensed for use in adults and for many drug...
There have been numerous studies to show that many of the medicines used in children are used off-la...
Knowledge of drug administration in children and infants lags behind that of adults for many reasons...
textabstractInterest in pediatric pharmacology has increased over the past two decades. With few exc...
The new drugs introduction in practice demands long multistage preliminary studying of efficacy and ...
Children were acknowledged as ‘therapeutic or pharmaceutical orphans’ in 1960s, since then there has...
Most drugs lack information on their safe and effective use in children. This dilemma limits the num...
Children often have to accept treatments based on what is known to work in adults. Many efforts are ...
Purpose Few data on the efficacy and safety of drugs in children are available as in the past, these...
Ethics and recruitment issues Evidence-based medicine and healthcare are the pillar of optimal medic...
Drug therapy is a very powerful tool to improve the medical outcome of children. Despite this fact, ...
Despite international initiatives to promote clinical research in pediatrics, there are still many g...
Purpose A dearth in pediatric drug development often leaves pediatricians with no alternative but to...
the present review is devoted to an actual problem of safety of pharmacotherapy in clinical practice...
This paper is focused on the most prominent problems of the contemporary pediatric pharmacotherapy: ...
textabstractMany commercially available drugs are only licensed for use in adults and for many drug...
There have been numerous studies to show that many of the medicines used in children are used off-la...
Knowledge of drug administration in children and infants lags behind that of adults for many reasons...
textabstractInterest in pediatric pharmacology has increased over the past two decades. With few exc...