John M Zajecka,1,2 Arielle D Stanford,3 Asli Memisoglu,4 William F Martin,5 Sanjeev Pathak3 1Department of Psychiatry, Rush University Medical Center, Chicago, IL, USA; 2Psychiatric Medicine Associates, LLC, Skokie, IL, USA; 3Department of Clinical Research, Alkermes, Inc., Waltham, MA, USA; 4Department of Biostatistics, Alkermes, Inc., Waltham, MA, USA; 5Clinical Operations, Alkermes, Inc., Waltham, MA, USA Background: The endogenous opioid system is a fundamental regulator of mood in humans. Previously reported clinical trials have demonstrated the efficacy of the investigational agent buprenorphine/samidorphan (BUP/SAM) combination, an opioid-system modulator, for the adjunctive treatment of major depressive disorder. We present here a...
Background: Randomized controlled clinical trials that have investigated minocycline as an adjunctiv...
The definitive version is available at www.blackwell-synergy.comAIMS: To assess the efficacy of bupr...
AIMS: The clinical effectiveness of buprenorphine-naloxone (bup-nx) and clonidine for opioid detoxif...
Although opioids have known antidepressant activity, their use in major depressive disorder (MDD) ha...
Introduction: Past trials of buprenorphine (BUP) in the treatment of major depressive disorder (MDD)...
BACKGROUND: Numerous reports have suggested that buprenorphine may have antidepressant effects. Many...
Background: The combination of buprenorphine, a partial mu-opioid receptor agonist and a functional ...
Although several pharmacological options to treat depression are currently available, approximately ...
Although several pharmacological options to treat depression are currently available, approximately ...
The present study aimed at investigating the effectiveness and tolerability of -bupropion hydrochlor...
Modulation of the opioid system has re-emerged as a potential therapeutic avenue for treating depres...
Yoshifumi Koshino,1 Won-Myong Bahk,2 Hideaki Sakai,3 Takayuki Kobayashi4 1Iris Medical Clinic, Kanaz...
10.1080/17425255.2018.1459564Expert Opinion on Drug Metabolism & Toxicology144475-48
Our goal was to determine whether treatment of depressive symptoms with escitalopram during buprenor...
Zoë Zuilhof, Sandhaya Norris, Claude Blondeau, Pierre Tessier, Pierre Blier Department of Psyc...
Background: Randomized controlled clinical trials that have investigated minocycline as an adjunctiv...
The definitive version is available at www.blackwell-synergy.comAIMS: To assess the efficacy of bupr...
AIMS: The clinical effectiveness of buprenorphine-naloxone (bup-nx) and clonidine for opioid detoxif...
Although opioids have known antidepressant activity, their use in major depressive disorder (MDD) ha...
Introduction: Past trials of buprenorphine (BUP) in the treatment of major depressive disorder (MDD)...
BACKGROUND: Numerous reports have suggested that buprenorphine may have antidepressant effects. Many...
Background: The combination of buprenorphine, a partial mu-opioid receptor agonist and a functional ...
Although several pharmacological options to treat depression are currently available, approximately ...
Although several pharmacological options to treat depression are currently available, approximately ...
The present study aimed at investigating the effectiveness and tolerability of -bupropion hydrochlor...
Modulation of the opioid system has re-emerged as a potential therapeutic avenue for treating depres...
Yoshifumi Koshino,1 Won-Myong Bahk,2 Hideaki Sakai,3 Takayuki Kobayashi4 1Iris Medical Clinic, Kanaz...
10.1080/17425255.2018.1459564Expert Opinion on Drug Metabolism & Toxicology144475-48
Our goal was to determine whether treatment of depressive symptoms with escitalopram during buprenor...
Zoë Zuilhof, Sandhaya Norris, Claude Blondeau, Pierre Tessier, Pierre Blier Department of Psyc...
Background: Randomized controlled clinical trials that have investigated minocycline as an adjunctiv...
The definitive version is available at www.blackwell-synergy.comAIMS: To assess the efficacy of bupr...
AIMS: The clinical effectiveness of buprenorphine-naloxone (bup-nx) and clonidine for opioid detoxif...