Glutamate is the major excitatory neurotransmitter in the brain. Its release and eventual recycling are key to rapid sustained neural activity. We have paired the gfap promoter region with the glutamate reporter molecule, iGluSnFR, to drive expression in glial cells throughout the nervous system. Tg(gfap:iGluSnFR) is expressed on the glial membrane of Müller glia cells in the retina, which rapidly respond to stimulation and the release of extracellular glutamate. As glial cells are associated with most, if not all, synapses, Tg(gfap:iGluSnFR) is a novel and exciting tool to measure neuronal activity and extracellular glutamate dynamics in many regions of the nervous system. Glutamate is the major excitatory neurotransmitter in the brain....
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. An accur...
This is the final version of the article. Available from Springer Nature via the DOI in this record....
The strength of an excitatory synapse depends on its ability to release glutamate and on the density...
Glutamate is the major excitatory neurotransmitter in the brain. Its release and eventual recycling ...
The rapid removal of synaptically-released glutamate is essential to maintain fast excitatory chemic...
The rapid removal of synaptically-released glutamate is essential to maintain fast excitatory chemic...
Current techniques for monitoring GABA (γ-aminobutyric acid), the primary inhibitory neurotransmitte...
Glutamate, a primary excitatory neurotransmitter, provides us key understanding of the signaling of ...
Photoreceptor ribbon synapses tonically release glutamate. To ensure efficient signal transmission a...
System xc– is an amino acid transporter that enables the transfer of intracellular glutamate in exch...
I have used the fluorescent reporter iGlusnFR to observe glutamate release from bipolar cell (BC) te...
System xc– is an amino acid transporter that enables the transfer of intracellular glutamate in exch...
System xc– is an amino acid transporter that enables the transfer of intracellular glutamate in exch...
AbstractA fluorometric procedure to image release of the neurotransmitter glutamate from living reti...
Retinal waves, the spontaneous patterned neural activities propagating among developing retinal gang...
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. An accur...
This is the final version of the article. Available from Springer Nature via the DOI in this record....
The strength of an excitatory synapse depends on its ability to release glutamate and on the density...
Glutamate is the major excitatory neurotransmitter in the brain. Its release and eventual recycling ...
The rapid removal of synaptically-released glutamate is essential to maintain fast excitatory chemic...
The rapid removal of synaptically-released glutamate is essential to maintain fast excitatory chemic...
Current techniques for monitoring GABA (γ-aminobutyric acid), the primary inhibitory neurotransmitte...
Glutamate, a primary excitatory neurotransmitter, provides us key understanding of the signaling of ...
Photoreceptor ribbon synapses tonically release glutamate. To ensure efficient signal transmission a...
System xc– is an amino acid transporter that enables the transfer of intracellular glutamate in exch...
I have used the fluorescent reporter iGlusnFR to observe glutamate release from bipolar cell (BC) te...
System xc– is an amino acid transporter that enables the transfer of intracellular glutamate in exch...
System xc– is an amino acid transporter that enables the transfer of intracellular glutamate in exch...
AbstractA fluorometric procedure to image release of the neurotransmitter glutamate from living reti...
Retinal waves, the spontaneous patterned neural activities propagating among developing retinal gang...
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. An accur...
This is the final version of the article. Available from Springer Nature via the DOI in this record....
The strength of an excitatory synapse depends on its ability to release glutamate and on the density...