The mitochondrial genome is an evolutionarily persistent and cooperative component of metazoan cells that contributes to energy production and many other cellular processes. Despite sharing the same host as the nuclear genome, the multi-copy mitochondrial DNA (mtDNA) follows very different rules of replication and transmission, which translate into differences in the patterns of selection. On one hand, mtDNA is dependent on the host for its transmission, so selections would favour genomes that boost organismal fitness. On the other hand, genetic heterogeneity within an individual allows different mitochondrial genomes to compete for transmission. This intra-organismal competition could select for the best replicator, which does not necessar...
Many years of extensive studies of metazoan mitochondrial genomes have es-tablished differences in g...
Mitochondria are essential subcellular organelles containing an extranuclear genome (mtDNA). Mutatio...
Diverse eukaryotic taxa carry facultative heritable symbionts, microbes that are passed from mother ...
Mitochondrial genomes compete for transmission from mother to progeny. We explored this competition ...
The peculiar biology of mitochondrial DNA (mtDNA) potentially has detrimental consequences for organ...
Metazoans exist only with a continuous and rich supply of chemical energy from oxidative phosphoryla...
Despite its functional conservation, the mitochondrial genome (mtDNA) presents strikingly different ...
Mitochondria, the product of an ancient endosymbiotic event are pivotal to eukaryotic cells by synth...
The replication of mitochondrial DNA (mtDNA) is not under strict control of the nucleus. Therefore, ...
Mutations of mitochondrial DNA (mtDNA) are frequent in humans and are implicated in many different t...
BACKGROUND: The endosymbiosis of an alpha-proteobacterium and a eubacterium a billion years ago pave...
none7Despite its functional conservation, mtDNA presents strikingly different features among eukaryo...
Assuming that fathers never transmit mitochondrial DNA (mtDNA) to their offspring, mitochondrial mut...
Since the unexpected discovery that mitochondria contain their own distinct DNA molecules, studies o...
Since the unexpected discovery that mitochondria contain their own distinct DNA molecules, studies o...
Many years of extensive studies of metazoan mitochondrial genomes have es-tablished differences in g...
Mitochondria are essential subcellular organelles containing an extranuclear genome (mtDNA). Mutatio...
Diverse eukaryotic taxa carry facultative heritable symbionts, microbes that are passed from mother ...
Mitochondrial genomes compete for transmission from mother to progeny. We explored this competition ...
The peculiar biology of mitochondrial DNA (mtDNA) potentially has detrimental consequences for organ...
Metazoans exist only with a continuous and rich supply of chemical energy from oxidative phosphoryla...
Despite its functional conservation, the mitochondrial genome (mtDNA) presents strikingly different ...
Mitochondria, the product of an ancient endosymbiotic event are pivotal to eukaryotic cells by synth...
The replication of mitochondrial DNA (mtDNA) is not under strict control of the nucleus. Therefore, ...
Mutations of mitochondrial DNA (mtDNA) are frequent in humans and are implicated in many different t...
BACKGROUND: The endosymbiosis of an alpha-proteobacterium and a eubacterium a billion years ago pave...
none7Despite its functional conservation, mtDNA presents strikingly different features among eukaryo...
Assuming that fathers never transmit mitochondrial DNA (mtDNA) to their offspring, mitochondrial mut...
Since the unexpected discovery that mitochondria contain their own distinct DNA molecules, studies o...
Since the unexpected discovery that mitochondria contain their own distinct DNA molecules, studies o...
Many years of extensive studies of metazoan mitochondrial genomes have es-tablished differences in g...
Mitochondria are essential subcellular organelles containing an extranuclear genome (mtDNA). Mutatio...
Diverse eukaryotic taxa carry facultative heritable symbionts, microbes that are passed from mother ...