Introduction: Cerebral cavernous malformations (CCMs; OMIM 116860) are enlarged vascular cavities without intervening brain parenchyma whose estimated prevalence in the general population is between 0.1% and 0.5%. Familial CCM is an autosomal dominant disease with incomplete clinical and radiological penetrance. Three genes have been linked to development of the lesions: CCM1/KRIT1, CCM2/MGC4607, and CCM3/PDCD10. Development: The aetiological mutation is not detected in a large percentage of cases and new approaches are therefore needed. The aim of this review is to analyse current molecular techniques and the possible mutations or variations which can be detected in a molecular genetics or molecular biology laboratory. Likewise, we will an...
Wide comprehension of genetic features of cerebral cavernous malformations (CCM) represents the star...
Cerebral cavernous malformations (CCMs) are vascular malformations mostly located within the central...
BACKGROUND: Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central...
Resumen: Introducción: Las malformaciones cavernosas cerebrales (CCM; OMIM 116860) son engrosamient...
Cerebral cavernous malformations (CCMs; OMIM 116860) are enlarged vascular cavities without interven...
[Objective] To study the molecular genetic and clinical features of cerebral cavernous malformations...
Cerebral cavernous malformations (CCM) can occur either as sporadic or familial form with autosomal ...
Cerebral cavernous malformations (CCM) are vascular lesions which affect up to 0.5% of the general p...
Cerebral cavernous malformations (CCM) can occur either as sporadic or familial form with autosomal ...
Cerebral cavernous malformations (CCMs) are lesions affecting brain microvessels. The pathogenesis i...
Objective: To study the molecular genetic and clinical features of cerebral cavernous malformations ...
Journal Article; Research Support, Non-U.S. Gov't;OBJECTIVE To study the molecular genetic and clin...
Cerebral cavernous malformations (CCMs) are a diffuse cerebrovascular disease affecting approximatel...
Cerebral cavernous malformation (CCM) is a vascular malformation causing neurological problems, such...
Introduction: Cerebral cavernous malformation (CCM) is a vascular disorder characterized by the pres...
Wide comprehension of genetic features of cerebral cavernous malformations (CCM) represents the star...
Cerebral cavernous malformations (CCMs) are vascular malformations mostly located within the central...
BACKGROUND: Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central...
Resumen: Introducción: Las malformaciones cavernosas cerebrales (CCM; OMIM 116860) son engrosamient...
Cerebral cavernous malformations (CCMs; OMIM 116860) are enlarged vascular cavities without interven...
[Objective] To study the molecular genetic and clinical features of cerebral cavernous malformations...
Cerebral cavernous malformations (CCM) can occur either as sporadic or familial form with autosomal ...
Cerebral cavernous malformations (CCM) are vascular lesions which affect up to 0.5% of the general p...
Cerebral cavernous malformations (CCM) can occur either as sporadic or familial form with autosomal ...
Cerebral cavernous malformations (CCMs) are lesions affecting brain microvessels. The pathogenesis i...
Objective: To study the molecular genetic and clinical features of cerebral cavernous malformations ...
Journal Article; Research Support, Non-U.S. Gov't;OBJECTIVE To study the molecular genetic and clin...
Cerebral cavernous malformations (CCMs) are a diffuse cerebrovascular disease affecting approximatel...
Cerebral cavernous malformation (CCM) is a vascular malformation causing neurological problems, such...
Introduction: Cerebral cavernous malformation (CCM) is a vascular disorder characterized by the pres...
Wide comprehension of genetic features of cerebral cavernous malformations (CCM) represents the star...
Cerebral cavernous malformations (CCMs) are vascular malformations mostly located within the central...
BACKGROUND: Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central...