Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is detrimental to renal function. Non-esterified fatty acids (also known as free fatty acids, FFA) are especially harmful to the kidneys. A concerted, increased FFA uptake due to high fat diets, overexpression of fatty acid uptake systems such as the CD36 scavenger receptor and the fatty acid transport proteins, and a reduced β-oxidation rate underlie the intracellular lipid accumulation in non-adipose tissues. FFAs in excess can damage podocytes, proximal tubular epithelial cells and the tubulointerstitial tissue through various mechanisms, in particular by boosting the ...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic kidney disease...
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic kidney disease...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Obesity is an independent risk factor for chronic kidney disease (CKD). The mechanisms linking obesi...
Obesity is an independent risk factor for chronic kidney disease (CKD). The mechanisms linking obesi...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Chronic kidney disease (CKD) is associated with atherogenic dyslipidemia. Our aim was firstly to inv...
BackgroundThe kidney plays a central role in elimination of metabolic waste products and regulation ...
BackgroundThe kidney plays a central role in elimination of metabolic waste products and regulation ...
The prevalence of obesity is increasing worldwide and contributes to many health problems, including...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic kidney disease...
Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic kidney disease...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Obesity is an independent risk factor for chronic kidney disease (CKD). The mechanisms linking obesi...
Obesity is an independent risk factor for chronic kidney disease (CKD). The mechanisms linking obesi...
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and homeostas...
Chronic kidney disease (CKD) is associated with atherogenic dyslipidemia. Our aim was firstly to inv...
BackgroundThe kidney plays a central role in elimination of metabolic waste products and regulation ...
BackgroundThe kidney plays a central role in elimination of metabolic waste products and regulation ...
The prevalence of obesity is increasing worldwide and contributes to many health problems, including...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...
Obesity and dyslipidaemia are features of the metabolic syndrome and risk factors for chronic kidney...