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Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity

Maria Keller
Lydia Hopp
Xuanshi Liu
Tobias Wohland
Kerstin Rohde
Raffaella Cancello
Matthias Klös
Karl Bacos
Matthias Kern
Fabian Eichelmann
Arne Dietrich
Michael R. Schön
Daniel Gärtner
Tobias Lohmann
Miriam Dreßler
Michael Stumvoll
Peter Kovacs
Anna-Maria DiBlasio
Charlotte Ling
Hans Binder
Matthias Blüher
Yvonne Böttcher

January 2017

Objective/methods: DNA methylation plays an important role in obesity and related metabolic complica...

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

January 2016

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of...

DNA methylation of leptin and adiponectin promoters in children is reduced by the combined presence of obesity and insulin resistance

García Cardona, María del Carmen
Huang, Fengyang
Garcia-Vivas, Jessica María
Lopez-Camarillo, Cesar
del Rio Navarro, Blanca E.
Navarro Olivos, Efraín
Hong-Chong, Enrique
Bolaños-Jiménez, Francisco
Marchat, Laurence A.

January 2014

International audienceOBJECTIVE: Epigenetic alterations have been suggested to be associated with ob...

Epigenetic markers to further understand insulin resistance

Ling, Charlotte
Rönn, Tina

November 2016

Epigenetic variation in human adipose tissue has been linked to type 2 diabetes and its related risk...

Genome-wide DNA methylation pattern in visceral adipose tissue differentiates insulin-resistant from insulin-sensitive obese subject

Crujeiras, Ana B.
Diaz-Lagares, Angel
Moreno-Navarrete, J. M.
Sandoval, Juan
Hervas, David
Gomez, A.
Ricart Engel, Wifredo
Casanueva, Felipe F.
Esteller, Manel
Fernandez-Real, J. M.

Elucidating the potential mechanisms involved in the detrimental effect of excess body weight on ins...

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes.

Barajas-Olmos, Francisco
Centeno-Cruz, Federico
Zerrweck, Carlos
Imaz-Rosshandler, Iván
Martínez-Hernández, Angélica
Cordova, Emilio J
Rangel-Escareño, Claudia
Gálvez, Faustino
Castillo, Armando
Maydón, Hernán
Campos, Francisco
Maldonado-Pintado, Diana Gabriela
Orozco, Lorena

April 2018

BACKGROUND: Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D...

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

Francisco Barajas-Olmos
Federico Centeno-Cruz
Carlos Zerrweck
Iván Imaz-Rosshandler
Angélica Martínez-Hernández
Emilio J. Cordova
Claudia Rangel-Escareño
Faustino Gálvez
Armando Castillo
Hernán Maydón
Francisco Campos
Diana Gabriela Maldonado-Pintado
Lorena Orozco

February 2018

Abstract Background Obesity is a well-recognized risk factor for insulin resistance and type 2 diabe...

DNA methylation microarrays identify epigenetically regulated lipid related genes in obese patients with hypercholesterolemia

Płatek, Teresa
Polus, Anna
Góralska, Joanna
Raźny, Urszula
Gruca, Anna
Kieć-Wilk, Beata
Zabielski, Piotr
Kapusta, Maria
Słowińska-Solnica, Krystyna
Solnica, Bogdan
Malczewska-Malec, Małgorzata
Dembińska-Kieć, Aldona

October 2020

Background: Epigenetics can contribute to lipid disorders in obesity. The DNA methylation pattern ca...

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

January 2017

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of...

Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity

Maria Keller
Lydia Hopp
Xuanshi Liu
Tobias Wohland
Kerstin Rohde
Raffaella Cancello
Matthias Klös
Karl Bacos
Matthias Kern
Fabian Eichelmann
Arne Dietrich
Michael R. Schön
Daniel Gärtner
Tobias Lohmann
Miriam Dreßler
Michael Stumvoll
Peter Kovacs
Anna-Maria DiBlasio
Charlotte Ling
Hans Binder
Matthias Blüher
Yvonne Böttcher

January 2017

Objective/methods: DNA methylation plays an important role in obesity and related metabolic complica...

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

January 2016

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of...

DNA methylation of leptin and adiponectin promoters in children is reduced by the combined presence of obesity and insulin resistance

García Cardona, María del Carmen
Huang, Fengyang
Garcia-Vivas, Jessica María
Lopez-Camarillo, Cesar
del Rio Navarro, Blanca E.
Navarro Olivos, Efraín
Hong-Chong, Enrique
Bolaños-Jiménez, Francisco
Marchat, Laurence A.

January 2014

International audienceOBJECTIVE: Epigenetic alterations have been suggested to be associated with ob...

Genome-wide DNA methylation pattern in visceral adipose tissue differentiates insulin-resistant from insulin-sensitive obese subject

Crujeiras, Ana B.
Diaz-Lagares, Angel
Moreno-Navarrete, J. M.
Sandoval, Juan
Hervas, David
Gomez, A.
Ricart Engel, Wifredo
Casanueva, Felipe F.
Esteller, Manel
Fernandez-Real, J. M.

Elucidating the potential mechanisms involved in the detrimental effect of excess body weight on ins...

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes.

Barajas-Olmos, Francisco
Centeno-Cruz, Federico
Zerrweck, Carlos
Imaz-Rosshandler, Iván
Martínez-Hernández, Angélica
Cordova, Emilio J
Rangel-Escareño, Claudia
Gálvez, Faustino
Castillo, Armando
Maydón, Hernán
Campos, Francisco
Maldonado-Pintado, Diana Gabriela
Orozco, Lorena

April 2018

BACKGROUND: Obesity is a well-recognized risk factor for insulin resistance and type 2 diabetes (T2D...

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes

Francisco Barajas-Olmos
Federico Centeno-Cruz
Carlos Zerrweck
Iván Imaz-Rosshandler
Angélica Martínez-Hernández
Emilio J. Cordova
Claudia Rangel-Escareño
Faustino Gálvez
Armando Castillo
Hernán Maydón
Francisco Campos
Diana Gabriela Maldonado-Pintado
Lorena Orozco

February 2018

Abstract Background Obesity is a well-recognized risk factor for insulin resistance and type 2 diabe...

DNA methylation microarrays identify epigenetically regulated lipid related genes in obese patients with hypercholesterolemia

Płatek, Teresa
Polus, Anna
Góralska, Joanna
Raźny, Urszula
Gruca, Anna
Kieć-Wilk, Beata
Zabielski, Piotr
Kapusta, Maria
Słowińska-Solnica, Krystyna
Solnica, Bogdan
Malczewska-Malec, Małgorzata
Dembińska-Kieć, Aldona

October 2020

Background: Epigenetics can contribute to lipid disorders in obesity. The DNA methylation pattern ca...

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

January 2017

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of...

Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity

Maria Keller
Lydia Hopp
Xuanshi Liu
Tobias Wohland
Kerstin Rohde
Raffaella Cancello
Matthias Klös
Karl Bacos
Matthias Kern
Fabian Eichelmann
Arne Dietrich
Michael R. Schön
Daniel Gärtner
Tobias Lohmann
Miriam Dreßler
Michael Stumvoll
Peter Kovacs
Anna-Maria DiBlasio
Charlotte Ling
Hans Binder
Matthias Blüher
Yvonne Böttcher

January 2017

Objective/methods: DNA methylation plays an important role in obesity and related metabolic complica...

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

January 2016

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of...

DNA methylation of leptin and adiponectin promoters in children is reduced by the combined presence of obesity and insulin resistance

García Cardona, María del Carmen
Huang, Fengyang
Garcia-Vivas, Jessica María
Lopez-Camarillo, Cesar
del Rio Navarro, Blanca E.
Navarro Olivos, Efraín
Hong-Chong, Enrique
Bolaños-Jiménez, Francisco
Marchat, Laurence A.

January 2014

International audienceOBJECTIVE: Epigenetic alterations have been suggested to be associated with ob...