The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for humans. With the LNT model, any radiation exposure is assumed to increase one's risk of cancer. Based on the LNT model, others have predicted tens of thousands of deaths related to environmental exposure to radioactive material from nuclear accidents ( e.g ., Chernobyl) and fallout from nuclear weapons testing. Here, we introduce a mechanism-based model for low-dose, radiation-induced, stochastic effects (genomic instability, apoptosis, mutations, neoplastic transformation) that leads to a LNT relationship between the risk for neoplastic transformation and dose only in special cases. It is shown that nonlinear dose-response relationships for r...
Current guidelines for limiting exposure of humans to ionizing radiation are based on the linear-no-...
Over several decades, modelling the effects of ionizing radiation on biological system has relied on...
Epidemiologic studies of cancer incidence are insensitive at low doses (<10 cGy). For this reason i...
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for h...
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for h...
OAK - B135 This project final report summarizes modeling research conducted in the U.S. Department o...
New research data for low-dose, low- linear energy transfer (LET) radiation-induced, stochastic effe...
New research data for low-dose, low- linear energy transfer (LET) radiation-induced, stochastic effe...
International audienceThe linear no-threshold (LNT) model was introduced into the radiological prote...
A stochastic two-stage cancer model with clonal expansion was used to investigate the potential impa...
The public fear of radiation is in part driven by the Linear No Threshold Hypothesis (LNTH), or the ...
There are now several independent studies that indicate that the dose-response for the endpoint of r...
A protective apoptosis-mediated (PAM) process that is turned on in mammalian cells by low-dose photo...
A protective apoptosis-mediated (PAM) process that is turned on in mammalian cells by low-dose photo...
A stochastic two-stage cancer model with clonal expansion was used to investigate the potential impa...
Current guidelines for limiting exposure of humans to ionizing radiation are based on the linear-no-...
Over several decades, modelling the effects of ionizing radiation on biological system has relied on...
Epidemiologic studies of cancer incidence are insensitive at low doses (<10 cGy). For this reason i...
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for h...
The linear nonthreshold (LNT) model plays a central role in low-dose radiation risk assessment for h...
OAK - B135 This project final report summarizes modeling research conducted in the U.S. Department o...
New research data for low-dose, low- linear energy transfer (LET) radiation-induced, stochastic effe...
New research data for low-dose, low- linear energy transfer (LET) radiation-induced, stochastic effe...
International audienceThe linear no-threshold (LNT) model was introduced into the radiological prote...
A stochastic two-stage cancer model with clonal expansion was used to investigate the potential impa...
The public fear of radiation is in part driven by the Linear No Threshold Hypothesis (LNTH), or the ...
There are now several independent studies that indicate that the dose-response for the endpoint of r...
A protective apoptosis-mediated (PAM) process that is turned on in mammalian cells by low-dose photo...
A protective apoptosis-mediated (PAM) process that is turned on in mammalian cells by low-dose photo...
A stochastic two-stage cancer model with clonal expansion was used to investigate the potential impa...
Current guidelines for limiting exposure of humans to ionizing radiation are based on the linear-no-...
Over several decades, modelling the effects of ionizing radiation on biological system has relied on...
Epidemiologic studies of cancer incidence are insensitive at low doses (<10 cGy). For this reason i...