Junctional adhesion molecules (JAMs) are a family of adhesion molecules localized at the tight junction of polarized cells and on the cell surface of leukocytes. The last 20years of research in this field has shown that several members of the family play an important role in the regulation of cell polarity, endothelium permeability and leukocytes migration. They mediate these pleiotropic functions through a multitude of homophilic and heterophilic interactions with intrafamily and extrafamily partners. In this article, we review the current status of the JAM family and highlight their functional role in tight junction dynamics and leukocyte transmigration
Formation of tissue barriers by epithelial and endothelial cells requires neighbouring cells to inte...
AbstractTight junctions contribute to the paracellular barrier, the fence dividing plasma membranes,...
The recruitment of leukocytes from the vascular lumen to sites of inflammation is an integral part o...
Junctional adhesion molecules (JAMs) are a family of adhesion molecules localized at the tight junct...
Similar to epithelia, endothelial cells are linked to each other via intercellular junctional comple...
Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin super...
Junctional adhesion molecules (JAMs) of the immunoglobulin superfamily are important in the control ...
Junctional Adhesion Molecules (JAMs) have been described as major components of tight junctions in e...
The junctional adhesion molecule B (JAM-B) is a multifunctional transmembrane protein, which belongs...
Junctional complexes between endothelial cells form a dynamic barrier that hinders passive diffusion...
The junctional adhesion molecule-A (JAM-A) is a cell surface adhesion molecule expressed on platelet...
Tight junctions play a central role in the establishment of cell polarity in vertebrate endothelial ...
Junctional adhesion molecule (JAM) is an integral membrane protein that has been reported to colocal...
AbstractLeukocyte transendothelial migration into inflamed areas is regulated by the integrity of en...
Epithelia and endothelia separate different tissue compartments and protect multicellular organisms ...
Formation of tissue barriers by epithelial and endothelial cells requires neighbouring cells to inte...
AbstractTight junctions contribute to the paracellular barrier, the fence dividing plasma membranes,...
The recruitment of leukocytes from the vascular lumen to sites of inflammation is an integral part o...
Junctional adhesion molecules (JAMs) are a family of adhesion molecules localized at the tight junct...
Similar to epithelia, endothelial cells are linked to each other via intercellular junctional comple...
Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin super...
Junctional adhesion molecules (JAMs) of the immunoglobulin superfamily are important in the control ...
Junctional Adhesion Molecules (JAMs) have been described as major components of tight junctions in e...
The junctional adhesion molecule B (JAM-B) is a multifunctional transmembrane protein, which belongs...
Junctional complexes between endothelial cells form a dynamic barrier that hinders passive diffusion...
The junctional adhesion molecule-A (JAM-A) is a cell surface adhesion molecule expressed on platelet...
Tight junctions play a central role in the establishment of cell polarity in vertebrate endothelial ...
Junctional adhesion molecule (JAM) is an integral membrane protein that has been reported to colocal...
AbstractLeukocyte transendothelial migration into inflamed areas is regulated by the integrity of en...
Epithelia and endothelia separate different tissue compartments and protect multicellular organisms ...
Formation of tissue barriers by epithelial and endothelial cells requires neighbouring cells to inte...
AbstractTight junctions contribute to the paracellular barrier, the fence dividing plasma membranes,...
The recruitment of leukocytes from the vascular lumen to sites of inflammation is an integral part o...