Feminist interventions on the sex/gender question in neuroimaging research

Contains fulltext : 201814.pdf (publisher's version ) (Open Access)This paper contributes to this field first by reviewing some outstanding issues pertaining to the question of sex/gender in the human brain, with a special focus on neuroimaging data; second by proposing several methodological interventions for more accurately interrogating sex/gender differences; and third by applying these interventions to an examination of similarities and differences between women and men in major white matter tracts using diffusion MRI (dMRI) data from a publicly available neuroimaging dataset. The interventions we describe and apply here include running empirical tests of randomization control and permutation analyses to protect against false positives, calculating measures of both difference (i.e., effect size) and overlap/similarity between groups, and reporting null results. Lastly, we discuss our findings and implications for study design with the aim to create a template for greater transparency in sex/gender neuroscience.19 p