Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic-and intramacrophage-based assays | ORKG Ask

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High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.

Aulner, Nathalie
Danckaert, Anne
Rouault-Hardoin, Eline
Desrivot, Julie
Helynck, Olivier
Commere, Pierre-Henri
Munier-Lehmann, Hélène
Späth, Gerald F
Shorte, Spencer L
Milon, Geneviève
Prina, Eric

April 2013

International audienceBACKGROUND/OBJECTIVES:Human leishmaniases are parasitic diseases causing sever...

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays.

Sarah L Berry
Hamza Hameed
Anna Thomason
Marissa L Maciej-Hulme
Somaia Saif Abou-Akkada
Paul Horrocks
Helen P Price

July 2018

The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an...

Development of NanoLuc-PEST expressing <i>Leishmania mexicana</i> as a new drug discovery tool for axenic- and intramacrophage-based assays

Sarah L. Berry (5508476)
Hamza Hameed (5508482)
Anna Thomason (3558581)
Marissa L. Maciej-Hulme (5508479)
Somaia Saif Abou-Akkada (5508485)
Paul Horrocks (49038)
Helen P. Price (183336)

July 2018

<div><p>The protozoan parasite <i>Leishmania</i> causes leishmaniasis; a spectrum of diseases of whi...

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays.

Berry, SL
Hameed, H
Thomason, A
Maciej-Hulme, ML
Saif Abou-Akkada, S
Horrocks, P
Price, HP

July 2018

The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an...

Development and validation of a novel <i>Leishmania donovani</i> screening cascade for high-throughput screening using a novel axenic assay with high predictivity of Leishmanicidal intracellular activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David W.

September 2015

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

Development and validation of a novel <i>Leishmania donovani</i> screening cascade for high-throughput screening using a novel axenic assay with high predictivity of Leishmanicidal intracellular activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David W.

September 2015

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

RESEARCH ARTICLE Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of

Leishmanicidal Intracellular Activity
Andrea Nühs
Manu De Rycker
Sujatha Manthri
Eamon Comer
Christina A. Scherer
Stuart L. Schreiber
Jean-robert Ioset
David W. Gray

August 2016

Visceral leishmaniasis is an important parasitic disease of the developing world with a lim-ited ars...

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David Michael

February 2017

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

Development and validation of a novel <i>Leishmania donovani</i> screening cascade for high-throughput screening using a novel axenic assay with high predictivity of Leishmanicidal intracellular activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David W.

September 2015

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.

Aulner, Nathalie
Danckaert, Anne
Rouault-Hardoin, Eline
Desrivot, Julie
Helynck, Olivier
Commere, Pierre-Henri
Munier-Lehmann, Hélène
Späth, Gerald F
Shorte, Spencer L
Milon, Geneviève
Prina, Eric

April 2013

International audienceBACKGROUND/OBJECTIVES:Human leishmaniases are parasitic diseases causing sever...

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.

Aulner, Nathalie
Danckaert, Anne
Rouault-Hardoin, Eline
Desrivot, Julie
Helynck, Olivier
Commere, Pierre-Henri
Munier-Lehmann, Hélène
Späth, Gerald F
Shorte, Spencer L
Milon, Geneviève
Prina, Eric

April 2013

International audienceBACKGROUND/OBJECTIVES:Human leishmaniases are parasitic diseases causing sever...

Development of NanoLuc-PEST expressing <i>Leishmania mexicana</i> as a new drug discovery tool for axenic- and intramacrophage-based assays

Sarah L. Berry (5508476)
Hamza Hameed (5508482)
Anna Thomason (3558581)
Marissa L. Maciej-Hulme (5508479)
Somaia Saif Abou-Akkada (5508485)
Paul Horrocks (49038)
Helen P. Price (183336)

July 2018

<div><p>The protozoan parasite <i>Leishmania</i> causes leishmaniasis; a spectrum of diseases of whi...

Development and validation of a novel <i>Leishmania donovani</i> screening cascade for high-throughput screening using a novel axenic assay with high predictivity of Leishmanicidal intracellular activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David W.

September 2015

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

Development and validation of a novel <i>Leishmania donovani</i> screening cascade for high-throughput screening using a novel axenic assay with high predictivity of Leishmanicidal intracellular activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David W.

September 2015

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

RESEARCH ARTICLE Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of

Leishmanicidal Intracellular Activity
Andrea Nühs
Manu De Rycker
Sujatha Manthri
Eamon Comer
Christina A. Scherer
Stuart L. Schreiber
Jean-robert Ioset
David W. Gray

August 2016

Visceral leishmaniasis is an important parasitic disease of the developing world with a lim-ited ars...

Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David Michael

February 2017

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

Development and validation of a novel <i>Leishmania donovani</i> screening cascade for high-throughput screening using a novel axenic assay with high predictivity of Leishmanicidal intracellular activity

Nühs, Andrea
De Rycker, Manu
Manthri, Sujatha
Comer, Eamon
Scherer, Christina A.
Schreiber, Stuart L.
Ioset, Jean-Robert
Gray, David W.

September 2015

Visceral leishmaniasis is an important parasitic disease of the developing world with a limited arse...

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.

Aulner, Nathalie
Danckaert, Anne
Rouault-Hardoin, Eline
Desrivot, Julie
Helynck, Olivier
Commere, Pierre-Henri
Munier-Lehmann, Hélène
Späth, Gerald F
Shorte, Spencer L
Milon, Geneviève
Prina, Eric

April 2013

International audienceBACKGROUND/OBJECTIVES:Human leishmaniases are parasitic diseases causing sever...

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.

Aulner, Nathalie
Danckaert, Anne
Rouault-Hardoin, Eline
Desrivot, Julie
Helynck, Olivier
Commere, Pierre-Henri
Munier-Lehmann, Hélène
Späth, Gerald F
Shorte, Spencer L
Milon, Geneviève
Prina, Eric

April 2013

International audienceBACKGROUND/OBJECTIVES:Human leishmaniases are parasitic diseases causing sever...