peer reviewedHuman brain imaging has revealed that acute pain results from activation of a network of brain regions, including the somatosensory, insular, prefrontal, and cingulate cortices. In contrast, many investigations report little or no alteration in brain activity associated with chronic pain, particularly neuropathic pain. It has been hypothesized that neuropathic pain results from misinterpretation of thalamocortical activity, and recent evidence has revealed altered thalamocortical rhythm in individuals with neuropathic pain. Indeed, it was suggested nearly four decades ago that neuropathic pain may be maintained by a discrete central generator, possibly within the thalamus. In this investigation, we used multiple brain imaging t...
Recent data suggests that in chronic pain there are changes in gray matter consistent with decreased...
Abstract Endogenous pain modulation in humans is frequently investigated with conditioned pain modul...
Central sensitization and network hyperexcitability of the nociceptive system is a basic mechanism o...
The neural mechanisms underlying the development and maintenance of chronic neuropathic pain remain ...
© 2018 Wiley Periodicals, Inc. Recurrent thalamocortical connections are integral to the gener...
© 2016 The Authors. The neural mechanisms underlying the development and maintenance of chronic ...
© 2018 The Authors The neural mechanisms underlying the development and maintenance of chronic pa...
International audienceHuman and animal imaging studies demonstrated that chronic pain profoundly alt...
peer reviewedTrigeminal neuropathic pain (TNP) and temporomandibular disorders (TMD) are thought to ...
Complex regional pain syndrome (CRPS) is a chronic neuropathic pain disorder that typically occurs i...
peer reviewedThere is increasing evidence relating thalamic changes to the generation and/or mainten...
It has been well-documented that the brain changes in states of chronic pain. Less is known about ch...
© 2018 the authors. Preclinical investigations have suggested that altered functioning of brains...
SummaryChronic pain and especially neuropathic pain are a major challenge to clinical practice and b...
Recent data suggests that in chronic pain there are changes in gray matter consistent with decreased...
Recent data suggests that in chronic pain there are changes in gray matter consistent with decreased...
Abstract Endogenous pain modulation in humans is frequently investigated with conditioned pain modul...
Central sensitization and network hyperexcitability of the nociceptive system is a basic mechanism o...
The neural mechanisms underlying the development and maintenance of chronic neuropathic pain remain ...
© 2018 Wiley Periodicals, Inc. Recurrent thalamocortical connections are integral to the gener...
© 2016 The Authors. The neural mechanisms underlying the development and maintenance of chronic ...
© 2018 The Authors The neural mechanisms underlying the development and maintenance of chronic pa...
International audienceHuman and animal imaging studies demonstrated that chronic pain profoundly alt...
peer reviewedTrigeminal neuropathic pain (TNP) and temporomandibular disorders (TMD) are thought to ...
Complex regional pain syndrome (CRPS) is a chronic neuropathic pain disorder that typically occurs i...
peer reviewedThere is increasing evidence relating thalamic changes to the generation and/or mainten...
It has been well-documented that the brain changes in states of chronic pain. Less is known about ch...
© 2018 the authors. Preclinical investigations have suggested that altered functioning of brains...
SummaryChronic pain and especially neuropathic pain are a major challenge to clinical practice and b...
Recent data suggests that in chronic pain there are changes in gray matter consistent with decreased...
Recent data suggests that in chronic pain there are changes in gray matter consistent with decreased...
Abstract Endogenous pain modulation in humans is frequently investigated with conditioned pain modul...
Central sensitization and network hyperexcitability of the nociceptive system is a basic mechanism o...