Comparison of within-individual change in antipsychotic utilization by antipsychotic prescribing pattern.

Each individual who had data on antipsychotic utilization at admission and discharge (n = 321) is represented by a point and grouped according to the prescribing pattern. Boxplots depict the distribution of this change. For individuals switching from polypharmacy to monotherapy (n = 136), the median change in utilization was -0.85 (interquartile range: -1.61 to -0.17). For individuals who remained on polypharmacy (n = 30), the median change in utilization was -0.48 (interquartile range: -1.45 to 0.17). For individuals who remained on monotherapy (n = 130), the median change in utilization was 0.00 (interquartile range: -0.43 to 0.50). For individuals switching from monotherapy to polypharmacy (n = 25), the median change in utilization was 0.80 (interquartile range: 0.15 to 1.43). Utilization was determined using the defined daily dose method.