ESX-1 mutant strains have lost hemolytic activity.
- Trang H. Phan (5625047)
- Lisanne M. van Leeuwen (5625050)
- Coen Kuijl (5625053)
- Roy Ummels (734424)
- Gunny van Stempvoort (2823650)
- Alba Rubio-Canalejas (5625056)
- Sander R. Piersma (252344)
- Connie R. Jiménez (252347)
- Astrid M. van der Sar (422976)
- Edith N. G. Houben (252320)
- Wilbert Bitter (185600)
Publication date
August 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Contact-dependent hemolysis of red blood cells (RBCs) by various M. marinum strains grown in the presence of Tween-80. Hemolysis was quantified by determining the OD405 absorption of the released hemoglobin. The data shown here is generated from two independent experiments, each time in triplicates. In A, the ESX-1 mutants and in B the complemented strains with restored hemolytic activity are shown. Significance is indicated, **** < 0.0001. Ctrl = control sample with PBS.</p
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