(A) A computational pipeline for systematically identifying RS sites. The pipeline contains three steps (Materials and methods). Candidate RS sites result after the first two steps, and sawtooth RS sites result after the third step. (B) A table lists the numbers of putative, candidate, and sawtooth RS sites and RS introns identified in three human cell lines (left panel). Hundreds of candidate RS sites were identified in more than two cell lines (right panel). (C) A schematic to illustrate 4sUDRB-seq captures recursive splicing. 4sU-labeled, newly synthesized, total RNAs from PA1, H9, and H9-differentiated FB cells were collected at different time points (T1, T2, …, Tn) after the commence of synchronized Pol II elongation, and transcripts w...
(A) Schematic indicating reads used for the RachetJunction (bottom) and RachetPair (top) methods to ...
peer reviewedNext-generation sequencing (NGS) technologiesbased transcriptomic profiling method ofte...
Thesis (Ph.D.)--University of Washington, 2020High throughput sequencing of RNA (RNA-seq) has become...
(A) The branch-point motif is enriched in the 20–50 bp window upstream of RS sites (purple line) and...
via an unconventional mechanism (atypically within the cytosol). This causes an open reading frame-...
(A) RS sites tend to reside in long introns. Introns with putative, candidate or sawtooth RS sites h...
SETTING:During endoplasmic reticulum (ER) stress, the endoribonuclease (RNase) Ire1α initiates remov...
With the recent, rapid progress in high throughput DNA sequencing technology, deep sequencing has ma...
RNA-Seq techniques generate hundreds of millions of short RNA reads using next-generation sequencing...
<p>Computational analysis was applied to identify the SNPs in the most likely regulatory regions of ...
<p>(A) Proportion of reads with a unique match to known genes (left), or known genes supplemented wi...
High-throughput RNA sequencing enables quantification of transcripts (both known and novel), exon/ex...
<div><p>Next-generation RNA sequencing (RNA-seq) maps and analyzes transcriptomes and generates data...
<p>RNA was extracted from PD leukocytes pre-DBS, post-DBS on stimulation and following one hour of e...
The discoveries of microRNAs and riboswitches, among others, have shown functional RNAs to be biolog...
(A) Schematic indicating reads used for the RachetJunction (bottom) and RachetPair (top) methods to ...
peer reviewedNext-generation sequencing (NGS) technologiesbased transcriptomic profiling method ofte...
Thesis (Ph.D.)--University of Washington, 2020High throughput sequencing of RNA (RNA-seq) has become...
(A) The branch-point motif is enriched in the 20–50 bp window upstream of RS sites (purple line) and...
via an unconventional mechanism (atypically within the cytosol). This causes an open reading frame-...
(A) RS sites tend to reside in long introns. Introns with putative, candidate or sawtooth RS sites h...
SETTING:During endoplasmic reticulum (ER) stress, the endoribonuclease (RNase) Ire1α initiates remov...
With the recent, rapid progress in high throughput DNA sequencing technology, deep sequencing has ma...
RNA-Seq techniques generate hundreds of millions of short RNA reads using next-generation sequencing...
<p>Computational analysis was applied to identify the SNPs in the most likely regulatory regions of ...
<p>(A) Proportion of reads with a unique match to known genes (left), or known genes supplemented wi...
High-throughput RNA sequencing enables quantification of transcripts (both known and novel), exon/ex...
<div><p>Next-generation RNA sequencing (RNA-seq) maps and analyzes transcriptomes and generates data...
<p>RNA was extracted from PD leukocytes pre-DBS, post-DBS on stimulation and following one hour of e...
The discoveries of microRNAs and riboswitches, among others, have shown functional RNAs to be biolog...
(A) Schematic indicating reads used for the RachetJunction (bottom) and RachetPair (top) methods to ...
peer reviewedNext-generation sequencing (NGS) technologiesbased transcriptomic profiling method ofte...
Thesis (Ph.D.)--University of Washington, 2020High throughput sequencing of RNA (RNA-seq) has become...