Additional file 2: of HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma

Figure S2. JNK or p38 inhibitors decreased the cell apoptosis. A, control shRNA/HSP90AA1 shRNA transfected MG-63 cells were treated with Dox (0.2 μg/mL) for 24 h with or without SP600125. Apoptosis was analyzed by measuring Annexin V-PE/PI positive cells by flow cytometric (n = 3; *, p < 0.05 versus control shRNA group). B, control shRNA/HSP90AA1 shRNA transfected MG-63 cells were treated with Dox (0.2 μg/mL) for 24 h with or without SB203580. Apoptosis was analyzed by measuring Annexin V-PE/PI positive cells by flow cytometric (n = 3; *, p < 0.05 versus control shRNA group). NS, not significant. (PDF 88 kb