Comparative expression of ABC transporters encoding genes after transient drug exposure of CBS138/ATCC2001 and BG2 strains.

The expression level was tested by qRT-PCR and data was measured by 2-ΔΔCT method in the presence of amphotericin B (A), fluconazole (B), caspofungin (C), and ketoconazole (D). Transporters behaved differently in these four conditions. Expression data were assessed by two-way ANOVA and statistical significant differences relative to untreated condition (YPD) were determined by Sidak's multiple comparisons test and are indicated as stars with p value <0.0001.