Additional file 5: of Mouse avatar models of esophageal squamous cell carcinoma proved the potential for EGFR-TKI afatinib and uncovered Src family kinases involved in acquired resistance

Figure S3. Pathway enrichment by RNA-Seq. Dot plots showing the enrichment results of KEGG pathway analysis for KYSE450-R versus KYSE450-P (A), EC109-R versus EC109-P (B), and PDX03-R versus PDX03-P (C), as detected by RNA-seq. The size of the dots indicates the number of genes enriched in the corresponding pathways. The color of the dots indicates the significance level of the enriched pathways, as represented by the value of Padj. (DOCX 549 kb