Transplantation of piPSC-derived osteoblast-like cells improved trabecular thickness and number in the left tibiae of the T3 group.

The range of ROI (1) was selected from the proximal metaphysis to the distal metaphysis in tibia. Left tibiae were subjected to cell transplantation, and right tibiae were maintained as internal control. C, control; T1, treatment 1; T2, treatment 2; T3, treatment 3. AB/ab: Values in the same site with different letters indicate significant differences (Duncan’s multiple range test). N = 3 in each group.