Maternal IgG present in the intervillous space crosses through distinct cell barriers, including syncytiotrophoblasts, the villous stroma which contains Hofbauer cells and fibroblasts, and fetal endothelial cells. Placental FcRn and FcγRIIIa are expressed in the outermost cell barrier of the villous tree: the syncytiotrophoblast. Hofbauer cells located in the villous stroma express FcγRI, FcγRIIb, and FcγRIIIa. Fetal endothelial cells express FcγRIIb but not FcRn. Fc, Fragment crystallizable; FcRn, Fc receptor neonatal; FcγRI, Fragment crystallizable gamma RI; FcγRIIb, Fragment crystallizable gamma RIIb; FcγRIIIa, Fragment crystallizable gamma RIIIa; IgG, Immunoglobulin.</p
The placenta is a fetal organ which has multiple functions. Insulin-like growth factor-I (IGF-I) has...
The transfer of maternal γ-globulin (IgG) provides the neonate with humoral immunity during early li...
The placenta is important for fetal development in mammals, and spatial transcriptomic profiling of ...
The human fetus acquires maternal IgG via the chorioallantoic placenta. Utilising antibodies against...
The human fetus acquires maternal IgG via the chorioallantoic placenta. Utilising antibodies against...
The human fetus is donated passive immunity, via the placenta, in the form of maternal IgG class ant...
To evaluate the potential role of human placental endothelial cells in the transport of IgG from mat...
The focus of this thesis is on the transport of maternal antibodies during pregnancy across the plac...
In primates, prenatal transfer of IgG from mother to offspring occurs predominantly across the place...
Further to the excellent overview on soluble Fcy receptors (FcyR) ’ by Fnidman et al. [1], it was th...
The neonatal FcR (FcRn) is a receptor that protects IgG from catabolism and is important in maintain...
The human fetus receives passive immunity via the chorioallantoic placenta in the form of maternal i...
The neonatal Fc receptor, (FcRn) is a transmembrane, heterodimeric glycoprotein with a structure sim...
THE ROLE OF THE NEONATAL FC RECEPTOR (FCRN) IN THE TRANSFER OF PASSIVE IMMUNITY AND MAINTENANCE OF A...
composed of two Fab portions and one Fc portion. The glycans attached to the Fc portions of IgG are ...
The placenta is a fetal organ which has multiple functions. Insulin-like growth factor-I (IGF-I) has...
The transfer of maternal γ-globulin (IgG) provides the neonate with humoral immunity during early li...
The placenta is important for fetal development in mammals, and spatial transcriptomic profiling of ...
The human fetus acquires maternal IgG via the chorioallantoic placenta. Utilising antibodies against...
The human fetus acquires maternal IgG via the chorioallantoic placenta. Utilising antibodies against...
The human fetus is donated passive immunity, via the placenta, in the form of maternal IgG class ant...
To evaluate the potential role of human placental endothelial cells in the transport of IgG from mat...
The focus of this thesis is on the transport of maternal antibodies during pregnancy across the plac...
In primates, prenatal transfer of IgG from mother to offspring occurs predominantly across the place...
Further to the excellent overview on soluble Fcy receptors (FcyR) ’ by Fnidman et al. [1], it was th...
The neonatal FcR (FcRn) is a receptor that protects IgG from catabolism and is important in maintain...
The human fetus receives passive immunity via the chorioallantoic placenta in the form of maternal i...
The neonatal Fc receptor, (FcRn) is a transmembrane, heterodimeric glycoprotein with a structure sim...
THE ROLE OF THE NEONATAL FC RECEPTOR (FCRN) IN THE TRANSFER OF PASSIVE IMMUNITY AND MAINTENANCE OF A...
composed of two Fab portions and one Fc portion. The glycans attached to the Fc portions of IgG are ...
The placenta is a fetal organ which has multiple functions. Insulin-like growth factor-I (IGF-I) has...
The transfer of maternal γ-globulin (IgG) provides the neonate with humoral immunity during early li...
The placenta is important for fetal development in mammals, and spatial transcriptomic profiling of ...