Additional file 8: of Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA
- Simon Heine (5718920)
- Markus Kleih (5718926)
- Neus Giménez (5718941)
- Kathrin Böpple (4332913)
- German Ott (216544)
- Dolors Colomer (1593736)
- Walter Aulitzky (5718935)
- Heiko van der Kuip (52857)
- Elisabeth Silkenstedt (5718938)
Publication date
September 2018
DOIAbstract
Figure S7. Palbociclib treatment induces autophagy but not after a short treatment period. (A) MCL cell line Jeko-1 was treated with 300 nM palbociclib for 24 h with or without 40 μM hydroxychloroquine. After treatment, autophagic vesicles were measured with Cyto-ID staining. (B) MCL cell line Mino was treated with 100 nM palbociclib for 6 h. After treatment autophagic vesicles were measured with Cyto-ID staining. (TIFF 1187 kb
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