Additional file 10: of Renal cancer: new models and approach for personalizing therapy
- Simona di Martino (5722790)
- Gabriele De Luca (244081)
- Ludovica Grassi (5722796)
- Giulia Federici (5722805)
- Romina Alfonsi (1549981)
- Michele Signore (129959)
- Antonio Addario (5722811)
- Laura De Salvo (3740305)
- Federica Francescangeli (5722814)
- Massimo Sanchez (183600)
- Valentina Tirelli (547526)
- Giovanni Muto (375271)
- Isabella Sperduti (85365)
- Steno Sentinelli (5722820)
- Manuela Costantini (5722823)
- Luca Pasquini (168695)
- Michele Milella (725941)
- Mustapha Haoui (5722826)
- Giuseppe Simone (5722829)
- Michele Gallucci (5722835)
- Ruggero De Maria (129963)
- Désirée Bonci (5722853)
Publication date
September 2018
DOIAbstract
Figure S7. (A) Two-way unsupervised hierarchical clustering of RPPA data of 2 G1, 7 G2, 8 G3, and 3 G4 ccRCC populations for the expression of stem cell markers reported as heatmap. (B) mRNA expression of SOX2 gene in G2, G3, and G4 ccRCC samples as assessed by RT-qPCR. Mean of three independent experiments is reported. RRN18S was used as endogenous control. *p < 0.05 (C) Representative immunofluorescence staining of tumor derived spheroids showing positivity for SOX2 (red). Merge is the over-lapping of SOX2 and DAPI staining. Confocal-microscope used Olympus, Fluoview FV1000 (Tokyo, Japan, http://www.olympus-global.com), magnification 40X. (PDF 246 kb
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