Mice were infected A) Proteinuria (n = 9–18 mice). (B) Kidney pathology with representative periodic acid-Schiff (PAS)-stained sections and immunofluorescence analysis of IgG2a and C3 deposits (n = 4–7 mice). (C) Glomerulonephritis scores (n = 3–6 mice). (D) Quantitation of glomerular IgG2a and C3 deposits defined by immunofluorescence (n = 4–7 mice). (E) Survival. (n = 8–16 mice; #, remaining mice were sacrificed when 50% mortality was attained). Plots summarize data from 1–2 independent experiments. Dots represent individual mice, horizontal bars indicate average, and asterisks statistical significance (*, p<0.05; **, p<0.01; ***, p<0.001).</p
<p>(A), Representative images of immunohistochemical staining of kidney sections from mice in the sa...
<p>A) Complete blood count with differential of LCMV-13 infected mice for platelet, neutrophil, lymp...
<p>(A) RV inoculation, challenge, and blood collection schedules in C57BL/6 mice. Mice were inoculat...
Mice were infected A) Anti-chromatin IgG2a autoantibodies detected by ELISA (sensitivity 5–10 ng/mL,...
Mice were infected A) Total serum IgG titers detected by ELISA (n = 9–18 mice). (B) Incidence and le...
<p>FVB or C57BL/6 mice were infected with 1–2×10<sup>6</sup> p.f.u. LCMV-13 and blood or tissue samp...
Mice were infected A) Number of total cells, B cells and T cells in spleen (n = 6 mice). (B) FACS an...
<p>(A) Serum samples from 8 month old female B6, B6.NZBc1, B6.NZBc13, B6.NZBc1c13 and NZB mice were ...
<p>FVB or C57BL/6 mice were infected with 1–2×10<sup>6</sup> p.f.u. and monitored for up to 11-days ...
Mice were infected A) Frequency and number of cDCs (CD11c+ PDCA-1−) and pDCs (CD11clow PDCA-1+) iden...
Frozen sections of kidneys from a one year old non-transgenic C57BL/6 mouse and from three thirteen ...
Spontaneous nephrotic mice (ICGN mice), a new mutant strain of mouse from outbred ICR, were clinical...
WT NZB mice, and NZB mice lacking either pDCs (Irf8−/−) or endosomal TLR signaling (Unc93b1 3d mutan...
<p>A: Kidney sections were stained with PAS. Images are representative for at least 12 mice in each ...
<p>Mice of the indicated genotype were injected with a lethal dose of 1×10<sup>5</sup> cfus Ca. At i...
<p>(A), Representative images of immunohistochemical staining of kidney sections from mice in the sa...
<p>A) Complete blood count with differential of LCMV-13 infected mice for platelet, neutrophil, lymp...
<p>(A) RV inoculation, challenge, and blood collection schedules in C57BL/6 mice. Mice were inoculat...
Mice were infected A) Anti-chromatin IgG2a autoantibodies detected by ELISA (sensitivity 5–10 ng/mL,...
Mice were infected A) Total serum IgG titers detected by ELISA (n = 9–18 mice). (B) Incidence and le...
<p>FVB or C57BL/6 mice were infected with 1–2×10<sup>6</sup> p.f.u. LCMV-13 and blood or tissue samp...
Mice were infected A) Number of total cells, B cells and T cells in spleen (n = 6 mice). (B) FACS an...
<p>(A) Serum samples from 8 month old female B6, B6.NZBc1, B6.NZBc13, B6.NZBc1c13 and NZB mice were ...
<p>FVB or C57BL/6 mice were infected with 1–2×10<sup>6</sup> p.f.u. and monitored for up to 11-days ...
Mice were infected A) Frequency and number of cDCs (CD11c+ PDCA-1−) and pDCs (CD11clow PDCA-1+) iden...
Frozen sections of kidneys from a one year old non-transgenic C57BL/6 mouse and from three thirteen ...
Spontaneous nephrotic mice (ICGN mice), a new mutant strain of mouse from outbred ICR, were clinical...
WT NZB mice, and NZB mice lacking either pDCs (Irf8−/−) or endosomal TLR signaling (Unc93b1 3d mutan...
<p>A: Kidney sections were stained with PAS. Images are representative for at least 12 mice in each ...
<p>Mice of the indicated genotype were injected with a lethal dose of 1×10<sup>5</sup> cfus Ca. At i...
<p>(A), Representative images of immunohistochemical staining of kidney sections from mice in the sa...
<p>A) Complete blood count with differential of LCMV-13 infected mice for platelet, neutrophil, lymp...
<p>(A) RV inoculation, challenge, and blood collection schedules in C57BL/6 mice. Mice were inoculat...