The average and the modal number of chromosome copies in the limiting distribution of on viable cells, for N = 8 and varying p and μ.</p
<p>χ<sup>2</sup> tests were performed in the available mutants under the null hypothesis of random d...
Distribution of the CNVRs on the chromosomes according to their state (gain, loss and complex).</p
<p>* r = 0.95</p><p>The mean allelic ratios for <i>CYP2D6</i> gene copy number.</p
The average number of chromosome copies for each N is represented by a dot on the x-axis.</p
The horizontal axis indicates the number of copies of the chromosome, and the vertical axis measures...
Each curve represents a given number of copies. A—D: Basic model () with N = 8 (except in D, which u...
1<p>The first row shows the modal number and the second the percentage of nuclei having a different ...
<p>(A) Distribution of chromosome number per cell is not significantly different from a log-normal d...
<p>Ploidy is <i>c</i> = 2<sup><i>n</i></sup> (<i>n</i> ≥ 1) in the polyploid cases, is the per-copy...
<p>The average copy numbers per cell of each human chromosome region are shown in correspondence to ...
Starting with a founder cell with 4 copies (A—E) or 2 copies (F—I). A, F: Normalized fraction of cel...
<p>Distribution of percentage of tumor cells with <i>MET</i> gene copy number ≥3 among different MET...
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p><i>(A)</i> Ongoing genomic instability with evolution of distinct sub-clones during tumour develo...
<p>In 40 (61%) of the 66 UM monosomy 3 and 8q aberrations occur together. Non-random distribution is...
<p>χ<sup>2</sup> tests were performed in the available mutants under the null hypothesis of random d...
Distribution of the CNVRs on the chromosomes according to their state (gain, loss and complex).</p
<p>* r = 0.95</p><p>The mean allelic ratios for <i>CYP2D6</i> gene copy number.</p
The average number of chromosome copies for each N is represented by a dot on the x-axis.</p
The horizontal axis indicates the number of copies of the chromosome, and the vertical axis measures...
Each curve represents a given number of copies. A—D: Basic model () with N = 8 (except in D, which u...
1<p>The first row shows the modal number and the second the percentage of nuclei having a different ...
<p>(A) Distribution of chromosome number per cell is not significantly different from a log-normal d...
<p>Ploidy is <i>c</i> = 2<sup><i>n</i></sup> (<i>n</i> ≥ 1) in the polyploid cases, is the per-copy...
<p>The average copy numbers per cell of each human chromosome region are shown in correspondence to ...
Starting with a founder cell with 4 copies (A—E) or 2 copies (F—I). A, F: Normalized fraction of cel...
<p>Distribution of percentage of tumor cells with <i>MET</i> gene copy number ≥3 among different MET...
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p><i>(A)</i> Ongoing genomic instability with evolution of distinct sub-clones during tumour develo...
<p>In 40 (61%) of the 66 UM monosomy 3 and 8q aberrations occur together. Non-random distribution is...
<p>χ<sup>2</sup> tests were performed in the available mutants under the null hypothesis of random d...
Distribution of the CNVRs on the chromosomes according to their state (gain, loss and complex).</p
<p>* r = 0.95</p><p>The mean allelic ratios for <i>CYP2D6</i> gene copy number.</p