Figure S2. NgBR is highly expressed in the tamoxifen-resistant T47D-TamR cells. (A) NgBR level was increased in T47D-TamR cells. Protein levels of Nogo-B, ERα, p53 and survivin in T47D and T47D-TamR cells were determined using western blot analysis. (B) Quantitative analysis of proteins presented in Additional file 2: Figure S2A was carried out using ImageJ and normalized to β-actin. Data are presented as fold changes of T47D-TamR compared to the T47D cells. The data are from three separate repeated experiments and are presented as the mean ± SD (*p < 0.05, n = 3). (PDF 155 kb
Increased transcription and expression of TLRs in COLO-205 tumor cells incubated with hCG. Semi-quan...
hCG and TLR ligands enhance chemo-resistance. Cell viability analysis on COLO-205 cells incubated wi...
Figure. S1. a Expression level of AFF3 and SLC116A14 in breast cancer tissues compared with noncance...
Figure S3. NgBR decreases the resistance of T47D-TamR to tamoxifen. (A) NgBR knockdown increases apo...
Figure S5. NgBR knockdown attenuated EGF-stimulated signaling and ERα phosphorylation in T47D-TamR c...
Figure S4. Sensitivity of T47D cells to tamoxifen is regulated by p53 and survivin (A) Knockdown of ...
Figure S1. MCF-7-TamR and T47D-TamR cells are resistant to 4-OHT. The 4-OHT resistant phenotype was ...
NgBR (NUS1) mRNA expression data were retrieved from GSE6532 database. Kaplan–Meier analysis reveale...
NgBR (NUS1) mRNA expression data were retrieved from a gene-expression profiling dataset (225071_x f...
Figure S6. Relapse-free survival (RFS) in patients with ERα-positive breast cancer (n = 343). NgBR (...
NgBR (NUS1) mRNA expression data were retrieved from a gene-expression profiling dataset (225071_x f...
Survivin (BIRC5) mRNA expression data were retrieved from a gene-expression profiling dataset (20209...
Survivin (BIRC5) mRNA expression data were retrieved from a gene-expression profiling dataset (20209...
Gene sets derived from T47D cells expressing WT PR and KR PR. These gene sets were used in the analy...
A Annexin V staining of MDA-MB-231 cells using flow cytometry to investigate apoptosis of MDA-MB-231...
Increased transcription and expression of TLRs in COLO-205 tumor cells incubated with hCG. Semi-quan...
hCG and TLR ligands enhance chemo-resistance. Cell viability analysis on COLO-205 cells incubated wi...
Figure. S1. a Expression level of AFF3 and SLC116A14 in breast cancer tissues compared with noncance...
Figure S3. NgBR decreases the resistance of T47D-TamR to tamoxifen. (A) NgBR knockdown increases apo...
Figure S5. NgBR knockdown attenuated EGF-stimulated signaling and ERα phosphorylation in T47D-TamR c...
Figure S4. Sensitivity of T47D cells to tamoxifen is regulated by p53 and survivin (A) Knockdown of ...
Figure S1. MCF-7-TamR and T47D-TamR cells are resistant to 4-OHT. The 4-OHT resistant phenotype was ...
NgBR (NUS1) mRNA expression data were retrieved from GSE6532 database. Kaplan–Meier analysis reveale...
NgBR (NUS1) mRNA expression data were retrieved from a gene-expression profiling dataset (225071_x f...
Figure S6. Relapse-free survival (RFS) in patients with ERα-positive breast cancer (n = 343). NgBR (...
NgBR (NUS1) mRNA expression data were retrieved from a gene-expression profiling dataset (225071_x f...
Survivin (BIRC5) mRNA expression data were retrieved from a gene-expression profiling dataset (20209...
Survivin (BIRC5) mRNA expression data were retrieved from a gene-expression profiling dataset (20209...
Gene sets derived from T47D cells expressing WT PR and KR PR. These gene sets were used in the analy...
A Annexin V staining of MDA-MB-231 cells using flow cytometry to investigate apoptosis of MDA-MB-231...
Increased transcription and expression of TLRs in COLO-205 tumor cells incubated with hCG. Semi-quan...
hCG and TLR ligands enhance chemo-resistance. Cell viability analysis on COLO-205 cells incubated wi...
Figure. S1. a Expression level of AFF3 and SLC116A14 in breast cancer tissues compared with noncance...