Infection of mice with 630Δ<i>erm</i> and <i>hpdC</i>::CT.
- Ian J. Passmore (5743520)
- Marine P. M. Letertre (5743523)
- Mark D. Preston (732916)
- Irene Bianconi (108469)
- Mark A. Harrison (5743526)
- Fauzy Nasher (5009036)
- Harparkash Kaur (63027)
- Huynh A. Hong (5743529)
- Simon D. Baines (412723)
- Simon M. Cutting (5743532)
- Jonathan R. Swann (139105)
- Brendan W. Wren (114209)
- Lisa F. Dawson (114195)
Publication date
September 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
a) A schematic of the C. difficile relapse infection in C57BL/6 mice. b) CFU counts enumerated from the faeces of individually caged animals (n = 5) infected with either wild-type C. difficile strain (630Δerm) or the corresponding p-cresol null mutant (hpdC::CT) over the duration of the primary infection (days 1–21) and relapse (days 1R-7R). c) CFU enumerated from the faeces day 4 post-infection and d) day 4 relapse. Mann Whitney U test was used to calculate significant differences between infection with wild-type C. difficile and the hpdC mutant marked *p<0.05. Graphs were produced in GraphPad Prism 6.0.</p
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