Decreased mortality and weight in CHIP-T246M rodents.
- Chang-he Shi (5315918)
- Carrie Rubel (5753825)
- Sarah E. Soss (744758)
- Rebekah Sanchez-Hodge (5753828)
- Shuo Zhang (30844)
- Sabrina C. Madrigal (5753831)
- Saranya Ravi (721874)
- Holly McDonough (5753834)
- Richard C. Page (1344438)
- Walter J. Chazin (112842)
- Cam Patterson (48482)
- Cheng-yuan Mao (5753837)
- Monte S. Willis (464831)
- Hai-Yang Luo (5753840)
- Yu-sheng Li (3476915)
- Donte A. Stevens (5753843)
- Mi-bo Tang (5315912)
- Pan Du (54309)
- Yao-he Wang (5753846)
- Zheng-wei Hu (5753849)
- Yu-ming Xu (5315924)
- Jonathan C. Schisler (256301)
Publication date
September 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Survival analysis of rats with the indicated genotypes (Mantel-Cox test) with the median survival (ms) indicated in weeks (w), N = 12 animals per genotype. Total body weight of (B) rats or (C) mice with the indicated genotypes over age represented by scatter plot and summarized by the mean ± 95% CI. For rats, N = 10 (per genotype); for mice, N = 30, 29, and 18 for T/T, T/M, and M/M, respectively. Tukey’s post hoc test: * p p p D) brain weight or (E) heart weight normalized to tibia length from mice with indicated genotypes represented by dot plot and summarized by the mean ± 95% CI: ††† corresponds to p < 0.001 comparing M/M to T/T and T/M.</p
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