CD63 expression depending on the intensity of the staining.

(A) Representative pictures of CD63 expression on cancer cells depending on the intensity of the staining. CD63 was mainly expressed on the cell membrane of gastric cancer cells, with a smaller amount in the cytoplasm. Pictures of score 0 and 1 are from patients with early gastric cancer, and both are well differentiated tubular adenocarcinoma. Picture of score 2+ and 3+ are from patients with advanced gastric cancer, and histologic type of score 2+ is well differentiated tubular adenocarcinoma, while histologic type of score 3+ is poorly differentiated adenocarcinoma. (B) Representative pictures of CD63 expression on stromal cells depending on the intensity of the staining. CD63 expression was mainly observed in the cytoplasm of stromal cells. Pictures of score 0 are from patients with early gastric cancer, and histologic type is well differentiated tubular adenocarcinoma. Pictures of score 1+ are from patients with advanced gastric cancer, and histologic type is poorly differentiated adenocarcinoma. Pictures of score 2+ are from patients with advanced gastric cancer, and histologic type is well differentiated tubular adenocarcinoma. Pictures of score 3+ are from patients with advanced gastric cancer, and histologic type is moderately differentiated tubular adenocarcinoma.