Predicted upstream regulators of differentially expressed genes between consecutive time points (DEGcts).

Time window specific identification of upstream analysis of the DEGcts using Ingenuity Pathway Analysis (IPA). The coloured circles are upstream regulators identified for each comparison of consecutive time points with an activation or inhibition Z score of respectively > 2.0 or S5 Table). Circle colours correspond to colours of the arrows linking the consecutive time points. Active upstream regulators are displayed at the top of the Figure and the inhibited upstream regulators are at the bottom of the Figure. The upstream regulators are grouped into four different categories: ‘Inflammatory factors’, ‘Transcription regulators’, ‘Hormones and growth factors’ and ‘Other’. Aldos = Aldosterone, D-gluc = D-glucose, Dinop = Dinoprost, Homocys = Homocysteine, NO = Nitric oxide, Pal ac = Palmitic acid, Prog = Progesterone, S-1-P = Shingosine-1-phosphate, Urso = Ursodeoxycholic acid.