Cellular miR-2909 ectopic expression augments oxidative stress.

(A) Glutathione oxidized (GSSG) to Glutathione reduced (GSH) ratio (GSSG to GSH) as a marker for oxidative stress, (B) flow-cytometric detection of reactive oxygen species (ROS) generation, (C) nitric oxide (NO) measurement and (D) superoxide dismutase(SOD) activity within human PBMCs transfected with miR-2909 expression vector compared with control null vector containing scrambled sequence after 48h incubation period. Each bar represents mean ± S.D of all the experiments performed in triplicate indicating 3 separate transfections, **p < 0.01, *p< 0.05 with respect to control.