Changes in hepatic oxylipins derived from arachidonic acid.
- Dennis R. Warner (5793875)
- Huilin Liu (346783)
- Shubha Ghosh Dastidar (5793878)
- Jeffrey B. Warner (5793881)
- Md Aminul Islam Prodhan (5793884)
- Xinmin Yin (284781)
- Xiang Zhang (19800)
- Ariel E. Feldstein (284627)
- Bin Gao (191656)
- Russell A. Prough (4163308)
- Craig J. McClain (470562)
- Irina A. Kirpich (5793887)
Publication date
September 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
A: Changes in the profile of LOX-dependent hydroxy-metabolites of AA. B: Levels of 11-HETE. C: Levels of 20-HETE (COX pathway). D: Levels of lipoxins (LOX pathway). E: Levels of AA-derived prostaglandins (COX pathway). F: Changes in epoxy- and dihydroxy-metabolites of AA derived via CYP/sEH pathway. G: Pearson correlation analysis between AA metabolites and markers of hepatic inflammation and injury: 8,9-DiHETrE and Mcp1 mRNA, and 11,12-DiHETrE and Hmgb1 mRNA. Data are presented as the mean ± SEM, Two way ANOVA, * P S2 Table.</p
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