Chronotropic effect of β-adrenergic agonists in bupivacaine-intoxicated rats.
- Jun Li (6494)
- Ran Duan (821258)
- Yingying Zhang (42910)
- Xin Zhao (71840)
- Yanxin Cheng (5807144)
- Yongxue Chen (5807147)
- Jinge Yuan (5807150)
- Hong Li (20183)
- Jianping Zhang (161794)
- Li Chu (459196)
- Dengyun Xia (5807153)
- Senming Zhao (357417)
Publication date
October 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Bupivacaine significantly reduced HR, while adrenalin and isoprenalin restored HR. (B) Bupivacaine prolonged PR interval, while isoprenalin and adrenalin showed no effect on PR interval. (C) Bupivacaine widened QRS duration, while isoprenalin and adrenalin showed no improvement on QRS duration. *P vs. baseline; †P vs, bupivacaine end; ‡P vs. bupivacaine + NS group.</p
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