Injection of gabazine into the MOB also increases RS neuron responses to olfactory stimulation.

(A) Top: schematic illustration of the brain showing stimulation, injection, and recording sites. Middle: responses of RS neurons to the electrical stimulation of the ON. A local injection of gabazine (0.1 mM) in the MOB increased the RS neuron responses to ON stimulation (5–10 μA). Each black trace is the mean of 10 individual responses (colored traces). Bottom: univariate scatterplot showing the normalized (as a percentage of control) EPSP amplitude in control, gabazine, and washout conditions for all animals. (B) Top: schematic illustration of the brain shows stimulation, injection, and recording sites. Middle: responses of RS neurons to the electrical stimulation of the MOB. Under control conditions, MOB stimulation did not induce responses in RS neurons. After a local injection of gabazine (0.1 mM) in the MOB, RS neurons responded to MOB stimulation (5–20 μA). Each black trace is the mean of 10 individual responses (colored traces). Bottom: univariate scatterplot showing the normalized (as a percentage of control) EPSP amplitude in control, gabazine, and washout conditions for all animals. An asterisk (*) indicates a statistically significant difference at the level p S1 Data. Di, diencephalon; EPSP, excitatory postsynaptic potential; LPal, lateral pallium; Mes, mesencephalon; MOB, main olfactory bulb; ON, olfactory nerve; Rh, rhombencephalon; RS, reticulospinal.