Engineered nanoparticles bind elapid snake venom toxins and inhibit venom-induced dermonecrosis - Fig 3

Jeffrey O’Brien (1768237)
Shih-Hui Lee (1999681)
José María Gutiérrez (62868)
Kenneth J. Shea (1306059)

Open link

Publication date

October 2018

DOI

10.1371/journal.pntd.0006736.g003

Publisher

Public Library of Science (PLoS)

Abstract

Nanoparticle binding to elapid snake venoms in concentrated human serum (A) Control experiments using the venom compositions of interest. (1) MW ladder. (1.1) Venom from Naja mossambica. (1.2) Venom from Bungarus caeruleus. (1.3) Venom from Bungarus fasciatus. (1.4) Venom from Naja haje. (1.5) Venom from Naja nivea. (1.6) Venom from Naja melonoleuca. (1.7) Venom from Naja sputatrix. (1.8) Venom from Dendroaspis polylepis. (B) NP selectivity results. (1) MW ladder. (2.0) Serum only control experiment. (2.1–2.8) NP selectivity results following the same venom-order described above. See S1–S10 Figs for full gel images.</p