(A) Methylation ratio of CpG site 7 of STXBP6 grouped by lung cancer stage. (B) Methylation ratios of CpG sites 1 and 38 of FZD10 grouped by lung cancer stage. (C) Methylation ratios of CpG site 6 of STXBP6 and CpG sites 4 and 20 of BCL6B grouped by tumor size. (D) Methylation ratio of CpG site 3 of STXBP6 grouped by patient age. (E) Methylation ratio of CpG site 12 of BCL6B grouped by lymph node metastasis status of patient. (F) Methylation ratios of CpG sites 3, 5, 8, 14, 20, and 22 of BCL6B grouped by patient sex. (G) Expression level of mRNA of the 4 candidate genes grouped by patient age.</p
Introduction. Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high meta...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
<div><p>Abnormal DNA methylation is known as playing an important role in the tumorgenesis. It is he...
Figure S2. Correlation coefficients for 6 CpGs showing positive correlation between patient’s age an...
Aberrant methylation of specific CpG sites at the promoter is widely responsible for genesis and dev...
<p>(A) List of genes potentially associated with aberrant methylation patterns in DLBCL. Boxplots vi...
<p>Only candidate genes which have a CpG island in their promoter region have been analyzed by MSP. ...
<p>The matched CpGs are sorted by their genomic context and then based upon the direction with which...
<p>Representation of the methylation percentages for CpG sites in Region B of the <i>SLC6a2</i> gene...
<p>Values are Person’s correlation coefficients and probabilities for the relationship between methy...
<p>DNA methylation levels (average β-values) (<b>A</b>) and mRNA expression levels (<b>B</b>) for th...
Additional file 6: Table S6. Gene expression datasets with paired cancer-normal lung tissues
Additional file 5. All relevant methylated sites of the five methylation-driven genes obtained from ...
UnrestrictedCell lines are widely used for studying DNA methylation in cancer. Their main applicatio...
<p>Human tumors undergo massive changes in DNA methylation. Recent studies showed that site-specific...
Introduction. Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high meta...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
<div><p>Abnormal DNA methylation is known as playing an important role in the tumorgenesis. It is he...
Figure S2. Correlation coefficients for 6 CpGs showing positive correlation between patient’s age an...
Aberrant methylation of specific CpG sites at the promoter is widely responsible for genesis and dev...
<p>(A) List of genes potentially associated with aberrant methylation patterns in DLBCL. Boxplots vi...
<p>Only candidate genes which have a CpG island in their promoter region have been analyzed by MSP. ...
<p>The matched CpGs are sorted by their genomic context and then based upon the direction with which...
<p>Representation of the methylation percentages for CpG sites in Region B of the <i>SLC6a2</i> gene...
<p>Values are Person’s correlation coefficients and probabilities for the relationship between methy...
<p>DNA methylation levels (average β-values) (<b>A</b>) and mRNA expression levels (<b>B</b>) for th...
Additional file 6: Table S6. Gene expression datasets with paired cancer-normal lung tissues
Additional file 5. All relevant methylated sites of the five methylation-driven genes obtained from ...
UnrestrictedCell lines are widely used for studying DNA methylation in cancer. Their main applicatio...
<p>Human tumors undergo massive changes in DNA methylation. Recent studies showed that site-specific...
Introduction. Lung adenocarcinoma (LAC) is the most frequent type of lung cancer and has a high meta...
DNA methylation is part of the epigenetic gene regulation complex, which is relevant for the pathoge...
<div><p>Abnormal DNA methylation is known as playing an important role in the tumorgenesis. It is he...