MVIIA effect on the relative gene expressions of Bcl-xl, Bax, caspase-9, caspase-12, caspase-8, caspase-3, and nNOS 48 h after spinal cord injury.

Mean relative gene expressions of Bcl-xl (a), Bax (b), caspase-9 (c), caspase-12 (d), caspase-8 (e), caspase-3 (f), and nNOS (g) (± standard deviation) in rats subjected to spinal cord injury associated with intrathecal administration of PBS (placebo, PLA rats) and MVIIA 10μM 4 h after SCI. Lowercases express statistical difference (a: PLA vs MVIIA, 0.72 ± 0.21 vs 0.37 ± 0.25, non-paired t test, p 0.05; d: PLA vs MVIIA, 0.89 ± 0.94 vs 0.61 ± 0.62, non-paired t test, p > 0.05; e: PLA vs MVIIA, 0.47 ± 0.13 vs 0.17 ± 0.13, Mann-Whitney test, p t test, p t test, p < 0.05).