Radiological evaluation of pathological nipple discharge (PND) in two patients.

(A) Normal galactogram in 78-years old woman with bloody PND. (B) Same patient’s axial thick slab reformat of the fat-suppressed non-enhanced T1-weighted sequence showing high signal ducts (arrow). (C) same level as 1B after gadolinium enhancement showing a small mass-lesion in the central area (arrow), proved to be a solitary intraductal papilloma at final histology. MRI was useful in detecting and locating the cause of symptoms. (D) Galactogram in 67-years old woman with PND showing multiple microdefects with a moth-eaten appearance, ductal wall irregularities and peripheral stenosis (arrows). (E) Same patient’s axial thick slab reformat of the fat-suppressed gadolinium enhanced T1-weighted sequence showing a segmental non-mass enhancement (triangular shaped with the apex at the nipple) corresponding to the galactogram. The final histology was multiple papillomatosis. MRI before oncoplastic conservative breast surgery did not offer additional information.