SC rotation angle is dependent on expansion characteristics of epithelial cells.

A Representative simulation of a minimally rotated SC upon completion of rotation. Adhesion parameter J(SCT, SCT) used: 0. B Representative simulation of an intermediately rotated SC upon completion of rotation. Adhesion parameter J(SCT, SCT) used: 0. C Representative simulation of a maximally rotated SC upon completion of rotation. Adhesion parameter J(SCT, SCT) used: 0. D Summary statistics of the change in areas of distal epithelial cells in each of simulations A, B and C. Vertical bars represent mean areas of distal epithelial cells. Colours correspond to the type of cells depicted in simulations. Non-solid bars represent values calculated at the start of simulations and solid bars represent values calculated at the conclusion of simulation (t = 2000 mcs). Dotted line represents α, final SC angle of each of the simulations. E Graphical illustration of calculation of rotation angle α. A straight line is connected between the CoM of the SC segments that are located at the two extreme ends of the SC. α is the angle between this straight line and the -x-axis.