Cytocompatibility of tested hydrogels.

(A) Metabolic activity of gingival fibroblasts grown on various hydrogels for 24 and 72 hours measured by the Cell Proliferation Kit I (MTT). The metabolic activity is shown as percentage relative to control, tissue culture plastic, which was set to 100%. (B) Cytotoxicity of the PEGylated fibrin hydrogel on gingival fibroblasts after 24 and 72 hours measured by the Cell Cytotoxicity Assay (LDH). The percentage of cytotoxicity was calculated in relation to the low (spontaneous LDH release from fibroblasts grown on tissue culture plastic) and high (fibroblasts grown on tissue culture plastic treated with 2% v/v triton-X-100) toxicity controls.