MOESM7 of Determinants of selection in yeast evolved by genome shuffling

Additional file 7: Figure S4. Genotyping of second generation segregants from backcrossing of R57 and wild type yeast suggest a model of SNP contributions to the SSL tolerance phenotype. Haploid (A) and diploid (B) isolates are scored in green for the genotypes indicated at the bottom. Growth in 85% SSL is scored in shades of blue on the right. Each row represents a single strain. Contribution to the phenotype of the indicated genotypes was inferred by multiple linear regression, yielding coefficients represented at the top in shades of red (diminishes fitness) to blue (increases fitness). Modeling of genetic interactions was attempted and the resulting coefficients are represented as circles at the top of the heatmaps. Growth in SSL predicted by the linear model is reported in shades of blue in the rightmost column, showing the level of agreement between the model and the data