PET-CT images.

(A) Coronal PET (red scale, cps x 10−3) and CT (gray scale) images of a control animal (C), low dose (LD, 3.5 mg/kg), and high dose (HD, 7 mg/kg). The bladder signal (arrow) is lower in treated animals than in controls. (B) Both furosemide doses led to a reduction in bladder SUVmean compared with the control group. (C) Bladder volume of the treated animals is slightly higher than the controls. (D) Non-significant differences were observed in kidney, bone marrow, small intestine and muscle uptake, although an increase in SUVmean was observed in the liver. *p < 0.05.