Additional file 1: of Efficacy and safety of nintedanib in advanced idiopathic pulmonary fibrosis

Table S1. Inclusion and exclusion criteria of the named patient use programme for nintedanib. IPF, idiopathic pulmonary fibrosis; ATS, American Thoracic Society; ERS, European Respiratory Society; JRS, Japanese Respiratory Society; ALAT, Latin American Thoracic Association; AST, aspartate aminotransferase; ALT, alanine aminotransferase; INR, international normalised ratio. Table S2. Odds ratios for the development of adverse events, adjusted for treatment duration, in the advanced group compared with the non-advanced idiopathic pulmonary fibrosis group. OR, odds ratio; CI, confidence interval. * Compared with the non-advanced group. Table S3. Comparison of time-to-occurrence of adverse events between the advanced and non-advanced idiopathic pulmonary fibrosis groups. Data are presented as median [interquartile range, weeks], unless otherwise indicated. URI, upper respiratory infection. Table S4. Odds ratios for the development of serious adverse events, adjusted for treatment duration, in the advanced group compared with the non-advanced idiopathic pulmonary fibrosis group. OR, odds ratio; CI, confidence interval. * Compared with the non-advanced group. (DOCX 24 kb