Comparison of standardized manual and Viridot plaque counts and neutralizing antibody titers.
- Leah C. Katzelnick (464055)
- Ana Coello Escoto (5892020)
- Benjamin D. McElvany (4011731)
- Christian Chávez (5892023)
- Henrik Salje (589157)
- Wensheng Luo (5892026)
- Isabel Rodriguez-Barraquer (233670)
- Richard Jarman (3608462)
- Anna P. Durbin (130760)
- Sean A. Diehl (240532)
- Derek J. Smith (247972)
- Stephen S. Whitehead (150702)
- Derek A. T. Cummings (116201)
Publication date
November 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
(A) Comparison of manual and Viridot counts of DENV3 plaques on C6/36 cells for six repeat titrations of a DENV3-positive antiserum by two analysts (A1 and A2). Linear regression lines are shown for each titration and analyst. The grey line indicates perfect correspondence. (B) PRNT50 titers with 95% confidence intervals for the six titrations counted by A1 and A2, manually and with Viridot. Resulting neutralization curves for A1 (C) and A2 (D) for the six titrations, counted either manually (solid lines) or with Viridot (dotted).</p
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