Human microglia cells are permissive to ZIKV infection.

Microglia cells were infected with ZIKV (MOI = 1) and expression of viral RNA was measured at different times post-infection by real-time RT-PCR (A). Viral replication was also determined by plaque assay analysis of culture supernatants of ZIKV-infected cells (B). Experiments were performed three times and errors bars represent standard error of the mean. The t-test was employed to analyze the differences between sets of data. *, P < 0.05.