Inflammasome activation of PBMCs and AMs in NSCLC and SCLC relative to controls.
- Ismini Lasithiotaki (191133)
- Eliza Tsitoura (2575855)
- Katerina D. Samara (5900327)
- Athina Trachalaki (4726929)
- Irini Charalambous (5900330)
- Nikolaos Tzanakis (14971)
- Katerina M. Antoniou (191138)
Publication date
October 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Induction of IL-1β and IL-18 secretion by LPS, LPS +ATP and LPS+ATP+ Caspase1 inhibitor I. LPS 250 pg/ml, 2hrs incubated at a 37oC/5% CO2 humidified incubator, followed by a 5mM ATP pulse for 20min at 37oC/5% CO2, in the presence or absence of 10μΜ caspase-1 inhibitor. a) IL-1β in PBMCs, b) IL-18 in PBMCs, c) IL-1β in AMs and d) IL-18 in AMs. Results are shown as mean+/- SD pg/ml, normalized to unstimulated.</p
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