UCSC genome browser tracks of enhancer-associated marks (H3K27ac, p300) on mouse E11.5 whole limb, forelimb, hindlimb (blue for Visel et al 2009; red for Coteny et al. 2012 and purple for Andrey et al, 2017) and mouse E10.5/1E11.5 craniofacial tissues (green for Attanasio et al 2013; ATAC-seq and H3K27ac for Minoux et al., 2018). Selected enhancer candidates are marked by an orange rectangle [24–28].</p
<p>(<b>A</b>) Box plots showing the AUROC estimated on the ten leave-one-out test sets, considering ...
Distant-acting tissue-specific enhancers, which regulate gene expression, vastly outnumber protein-c...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...
(A) A scheme of the HDAC9-TWIST1 locus. UCSC genome browser track represents genes and black bars re...
4C-seq interaction profiles of Twist1 and Hdac9 promoters as viewpoints in the forelimb and branchia...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...
Establishing causal links between non-coding variants and human phenotypes is an increasing challeng...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...
<p>BARs that were selected for enhancer assays, the limb-associated genes nearby, the limb phenotype...
Health Professions - Laboratory/Cellular: 3rd Place (The Ohio State University Denman Undergraduate ...
(A) Genomic coordinates and sequence alignment using either the bat or the chick sequence onto the m...
Distant-acting tissue-specific enhancers, which regulate gene expression, vastly outnumber protein-c...
Epigenetic modifications, transcription factor (TF) availability and chromatin conformation influenc...
SummaryEnhancers are distal regulatory elements that can activate tissue-specific gene expression an...
A major yet unresolved quest in decoding the human genome is the identification of the regulatory se...
<p>(<b>A</b>) Box plots showing the AUROC estimated on the ten leave-one-out test sets, considering ...
Distant-acting tissue-specific enhancers, which regulate gene expression, vastly outnumber protein-c...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...
(A) A scheme of the HDAC9-TWIST1 locus. UCSC genome browser track represents genes and black bars re...
4C-seq interaction profiles of Twist1 and Hdac9 promoters as viewpoints in the forelimb and branchia...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...
Establishing causal links between non-coding variants and human phenotypes is an increasing challeng...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...
<p>BARs that were selected for enhancer assays, the limb-associated genes nearby, the limb phenotype...
Health Professions - Laboratory/Cellular: 3rd Place (The Ohio State University Denman Undergraduate ...
(A) Genomic coordinates and sequence alignment using either the bat or the chick sequence onto the m...
Distant-acting tissue-specific enhancers, which regulate gene expression, vastly outnumber protein-c...
Epigenetic modifications, transcription factor (TF) availability and chromatin conformation influenc...
SummaryEnhancers are distal regulatory elements that can activate tissue-specific gene expression an...
A major yet unresolved quest in decoding the human genome is the identification of the regulatory se...
<p>(<b>A</b>) Box plots showing the AUROC estimated on the ten leave-one-out test sets, considering ...
Distant-acting tissue-specific enhancers, which regulate gene expression, vastly outnumber protein-c...
The transcription factor TWIST1 plays a vital role in mesoderm development, particularly in limb and...