Pathology of lung tissues in T-CNT-exposed mice.

Lung tissues at 12 months after T-CNT exposure were collected and tissue sections were stained with H&E. (A, B) Controls, (C, D) Low dose T-CNT, (E-G) High dose T-CNT. Change to the alveolar wall is shown (A-F). Macrophage accumulation in the alveolar space is shown (D-G). Photos are representative of each group. Scale bar: 100 μm (A, C, E), 50 μm (C, D, F, G). Arrow heads indicate T-CNT fibers (G). (H) SEM of the sediment of the dissolved lung tissue of a mouse exposed to T-CNT (high dose). Photos is representative of high dose group. Scale bar: 4 μm.