The indicated strains were transformed with centromeric (CEN) or 2µ plasmids encoding either wt, or one of the mutant α-syn genes under the strong GPD promoter. Shown is growth of transformants after incubation for 3 days at 30°C and 2 days at 25°C.</p
<p>Strains WT (STH2370 wild type), ΔSPI-3 (SPI-3<i><sup>−</sup></i>), ΔSPI-3/pBmgtC (<i>mgtC</i><sup...
<p>(A) The colony morphology of Δ<i>fpr1</i> mutant strains on complete media was not altered compar...
<p>(A) Asd4 physically interacts with the <i>GLN1</i> promoter <i>in vivo</i> following growth on GM...
The wt or strains A1-A4 were transformed with either CEN or 2μ plasmid, with or without the gene enc...
<p>(A) The effect of WT α-syn expression on the growth of three deletion strains (<i>elo1</i>Δ, <i>e...
WT, A2, or A3 cells were grown in liquid media until mid-log phase. For heat shock, wt cells were in...
Strains A3, A4 (A), or corresponding strain atg5Δ (B) were grown in liquid SD media lacking a nitrog...
(A) The A1-A4 strains, which lack the gene encoding Atg5, were monitored for α-syn mediated toxicity...
<p>A. Schematic representation of genomic region of <i>hld-</i>wild-type strain (WT) and two differe...
<p>(<b>A–D</b>) Growth of representative Δ<i>asdA</i> mutant strains complemented with <i>asdA</i> f...
<p>(A) NIH 3T3 cells stably expressing wild type or E633K p110β were plated in soft agar and colonie...
(A and B) Assessment of sporulation in spo73Δ (TC545, A) spo71Δ (TC581, B) overexpressing construct ...
<p>A and B) YL10-1, a <i>cdc34-2</i> temperature sensitive strain, bearing 2 µm plasmids encoding th...
<p>(<b>A</b>) WT (BY4741) and <i>hom6Δ</i> (YR001) strains transformed with vector (pRS313) and <i>h...
a<p>Strains deleted for these genes are listed in <a href="http://www.plosone.org/article/info:doi/1...
<p>Strains WT (STH2370 wild type), ΔSPI-3 (SPI-3<i><sup>−</sup></i>), ΔSPI-3/pBmgtC (<i>mgtC</i><sup...
<p>(A) The colony morphology of Δ<i>fpr1</i> mutant strains on complete media was not altered compar...
<p>(A) Asd4 physically interacts with the <i>GLN1</i> promoter <i>in vivo</i> following growth on GM...
The wt or strains A1-A4 were transformed with either CEN or 2μ plasmid, with or without the gene enc...
<p>(A) The effect of WT α-syn expression on the growth of three deletion strains (<i>elo1</i>Δ, <i>e...
WT, A2, or A3 cells were grown in liquid media until mid-log phase. For heat shock, wt cells were in...
Strains A3, A4 (A), or corresponding strain atg5Δ (B) were grown in liquid SD media lacking a nitrog...
(A) The A1-A4 strains, which lack the gene encoding Atg5, were monitored for α-syn mediated toxicity...
<p>A. Schematic representation of genomic region of <i>hld-</i>wild-type strain (WT) and two differe...
<p>(<b>A–D</b>) Growth of representative Δ<i>asdA</i> mutant strains complemented with <i>asdA</i> f...
<p>(A) NIH 3T3 cells stably expressing wild type or E633K p110β were plated in soft agar and colonie...
(A and B) Assessment of sporulation in spo73Δ (TC545, A) spo71Δ (TC581, B) overexpressing construct ...
<p>A and B) YL10-1, a <i>cdc34-2</i> temperature sensitive strain, bearing 2 µm plasmids encoding th...
<p>(<b>A</b>) WT (BY4741) and <i>hom6Δ</i> (YR001) strains transformed with vector (pRS313) and <i>h...
a<p>Strains deleted for these genes are listed in <a href="http://www.plosone.org/article/info:doi/1...
<p>Strains WT (STH2370 wild type), ΔSPI-3 (SPI-3<i><sup>−</sup></i>), ΔSPI-3/pBmgtC (<i>mgtC</i><sup...
<p>(A) The colony morphology of Δ<i>fpr1</i> mutant strains on complete media was not altered compar...
<p>(A) Asd4 physically interacts with the <i>GLN1</i> promoter <i>in vivo</i> following growth on GM...